Before Reason, there was ReBirth which was a huge hit with both MAC and PC. You could chain up to 32 patterns together of each instrument and have all four playing together for what would have been complete tunes back in the halcyon days of acid.
ReBirth was the first software emulation and paved way to million other virtual instruments. Despite its success, in 2005, it was announced that ReBirth was being discontinued. According to a statement released by Propellerhead they want to concentrate their efforts on more current products and on future projects.
Read more about this here: http://www.musictech.net/2017/11/rewind-propellerhead-rebirth-rb-338/