Simple solutions to simple problems are great, but sometimes simple solutions create additional problems. Instead of boosting the low end to bring out the bass guitar, try adding more to the mid-range. This will draw attention to the instrument and make it easier for the listener’s brain to process the sound. There are other more technical tips, like using harmonic distortion to make something sound more clear.
You can read more about professional techniques that might make your head turn here: http://theproaudiofiles.com/7-obscure-mixing-techniques/